Chinese Pharmacopoeia No. WS1-XG-031-2000
Protozoa: Gloydius ussuriensis or Deinagkistrodon acutus
Basic parameters: The active component of defibrase is a serine protease from the venom of Agkistrodon acutus or Agkistrodon acutus in China.
The molecular weight of the single component extracted is about 36KD.
Bioactivity: It can remove Arg-Gly bond in fibrinogen alpha chain, but has no effect on fibrinogen beta chain. drop
Fibrinase has the characteristics of thrombolysis, prevention of thrombosis and improvement of microcirculation.
Direction of application: acute cerebral infarction, myocardial infarction, sudden deafness, pulmonary embolism
